Can We Prevent, Delay, or Shorten the Course of Dementia?
2006

Can We Prevent or Delay Dementia?

publication Evidence: moderate

Author Information

Author(s): Willem A. Van Gool

Primary Institution: Academic Medical Centre, Amsterdam, Netherlands

Hypothesis

Is dementia a curse that is inescapably linked to old age?

Conclusion

The prevalence of dementia rises steeply with age, and while higher education and social class offer some protection, the effects are small.

Supporting Evidence

  • The prevalence of dementia in the year before death is up to 40%-60% in those over 90 years of age.
  • Nearly 80% of those dying over 95 years of age suffered from moderate or more severe cognitive impairment.
  • Higher social class reduced the risk of dying with dementia by only 2%.
  • Higher levels of education reduced the risk of dying with dementia by only 7%.

Takeaway

As people get older, more of them get dementia, and while being educated or from a higher social class helps a little, it doesn't stop it completely.

Methodology

The study analyzed a large population sample to assess the prevalence of dementia and cognitive impairment in the year before death.

Potential Biases

Confounding factors may bias the results, as proxies for cardiovascular prevention were not strong indicators.

Limitations

The observational nature of the study limits its ability to establish cause and effect.

Participant Demographics

The study focused on elderly individuals, particularly those over 90 years of age.

Digital Object Identifier (DOI)

10.1371/journal.pmed.0030430

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