Lung cancer in lifetime nonsmoking men – results of a case-control study in Germany
2001

Lung Cancer Risk in Nonsmoking Men

Sample size: 861 publication Evidence: moderate

Author Information

Author(s): Kreuzer M, Gerken M, Kreienbrock L, Wellmann J, Wichmann H E

Primary Institution: BfS – Federal Office of Radiation Protection

Hypothesis

What is the lung cancer risk for lifetime nonsmoking men in relation to various environmental and occupational factors?

Conclusion

Occupational carcinogens and indoor radon may contribute to lung cancer in nonsmoking men.

Supporting Evidence

  • The study included 58 cases of confirmed primary lung cancer and 803 controls.
  • A two-fold increased lung cancer risk was associated with jobs known to have lung carcinogens.
  • Radon exposure showed a close to significant trend for increased lung cancer risk.

Takeaway

This study looked at men who never smoked and found that certain jobs and radon exposure might increase their chances of getting lung cancer.

Methodology

A case-control study with interviews and radon measurements was conducted among 58 lung cancer cases and 803 controls.

Potential Biases

Potential recall bias in self-reported occupational history.

Limitations

The study may not account for all potential risk factors and had a relatively small sample size for cases.

Participant Demographics

Lifetime nonsmoking men in Germany.

Statistical Information

P-Value

0.052

Confidence Interval

1.0–5.0

Statistical Significance

p=0.052

Digital Object Identifier (DOI)

10.1054/bjoc.2000.1518

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