Polymorphism, selection and tandem duplication of transferrin genes in Atlantic cod (Gadus morhua) - Conserved synteny between fish monolobal and tetrapod bilobal transferrin loci
2011

Transferrin Genes in Atlantic Cod and Their Evolution

Sample size: 375 publication 10 minutes Evidence: high

Author Information

Author(s): Øivind Andersen, Maria Cristina De Rosa, Davide Pirolli, Ave Tooming-Klunderud, Petra E. Petersen, Carl André

Primary Institution: Nofima Marin

Hypothesis

The study investigates the polymorphism and selection of transferrin genes in Atlantic cod and their evolutionary significance.

Conclusion

The study provides evidence for positive selection and local adaptation in Atlantic cod populations based on transferrin gene polymorphisms.

Supporting Evidence

  • The Atlantic cod genome contains two tandem duplicated transferrin genes.
  • Polymorphisms in cod transferrin genes were linked to local adaptation.
  • Evidence of positive selection was indicated by a high dN/dS ratio.

Takeaway

Scientists studied genes in cod fish that help them fight infections and found that different groups of cod have adapted to their environments over time.

Methodology

The study involved identifying transferrin genes in the Atlantic cod genome, analyzing SNPs across various populations, and conducting statistical analyses to assess selection.

Limitations

The study did not investigate polymorphism in cod Tf2 across different populations.

Participant Demographics

The study included Atlantic cod collected from 14 different locations across the North Atlantic.

Statistical Information

P-Value

0.0013

Statistical Significance

p = 0.0013

Digital Object Identifier (DOI)

10.1186/1471-2156-12-51

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