A community effectiveness trial of strategies promoting intermittent preventive treatment with sulphadoxine-pyrimethamine in pregnant women in rural Burkina Faso
2008

Community Strategies to Improve Malaria Treatment in Pregnant Women

Sample size: 2550 publication 10 minutes Evidence: moderate

Author Information

Author(s): Gies Sabine, Coulibaly Sheick Oumar, Ouattara Florence Tiemegna, Ky Clotilde, Brabin Bernard John, D'Alessandro Umberto

Primary Institution: Institute of Tropical Medicine, Antwerp, Belgium

Hypothesis

Can a community-based promotion campaign effectively increase antenatal clinic attendance and sulphadoxine-pyrimethamine uptake among pregnant women in rural Burkina Faso?

Conclusion

The promotional campaign significantly increased IPTp coverage, but did not lead to improvements in maternal anaemia or birth weight outcomes.

Supporting Evidence

  • SP uptake was higher with community promotion (70%) than without (49%).
  • Peripheral and placental malaria rates were significantly lower in the intervention groups compared to the control.
  • Despite increased SP coverage, there was no significant difference in maternal anaemia or birth weight outcomes.

Takeaway

The study tried to help pregnant women get better malaria treatment by encouraging them to visit health clinics more often, but it didn't make a big difference in their health outcomes.

Methodology

The study involved a community promotion campaign and compared outcomes between women receiving IPTp-SP with and without additional promotional activities.

Potential Biases

Selection bias may have occurred due to non-random assignment of health centers to intervention groups.

Limitations

The study faced challenges in following up pregnant women due to high mobility and sub-optimal working conditions in health centers.

Participant Demographics

Participants were mainly young women (mean age 19.7 years) without formal education, mostly married and living within 5 km from the nearest health center.

Statistical Information

P-Value

0.014

Confidence Interval

95%CI 1.25–4.82

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1475-2875-7-180

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