Body weight and risk of soft-tissue sarcoma
1999

Body Weight and Risk of Soft-Tissue Sarcoma

Sample size: 1514 publication Evidence: moderate

Author Information

Author(s): Tavani A, Soler M, Vecchia C La, Negri E, Gallus S, Franceschi S

Primary Institution: Istituto di Ricerche Farmacologiche ‘Mario Negri’

Hypothesis

The study evaluates the relationship between body mass index (BMI) and the risk of soft-tissue sarcoma (STS).

Conclusion

The risk of soft-tissue sarcoma increases with higher body mass index.

Supporting Evidence

  • The study found that the risk of STS rose with BMI.
  • Multivariate odds ratios indicated a significant increase in risk for individuals with a BMI over 30 kg m–2.

Takeaway

If you weigh more, you might have a higher chance of getting a certain type of cancer called soft-tissue sarcoma.

Methodology

A case-control study was conducted with 217 incident STS cases and 1297 hospital controls.

Participant Demographics

Participants included men and women from Northern Italy.

Statistical Information

Confidence Interval

95% CI 1.06–11.55 for men; 95% CI 1.27–8.35 for women

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690781

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