Biological Behavior of Papillary Carcinoma of the Thyroid Including Squamous Cell Carcinoma Components and Prognosis of Patients Who Underwent Locally Curative Surgery
2012

Study of Papillary Thyroid Carcinoma with Squamous Cell Carcinoma Components

Sample size: 10 publication Evidence: moderate

Author Information

Author(s): Yasuhiro Ito, Mitsuyoshi Hirokawa, Takuya Higashiyama, Minoru Kihara, Chisato Tomoda, Yuuki Takamura, Kaoru Kobayashi, Akihiro Miya, Akira Miyauchi

Primary Institution: Kuma Hospital

Hypothesis

Can patients with papillary thyroid carcinoma having squamous cell carcinoma components survive after locally curative surgery?

Conclusion

Some patients with papillary thyroid carcinoma having squamous cell carcinoma components can survive for a prolonged period after locally curative surgery.

Supporting Evidence

  • Only 3 of 8 primary lesions were preoperatively diagnosed as having SCC components.
  • 7 patients survived for 8 to 43 months after diagnosis.
  • Adjuvant therapies were effective for local and distant recurrences in some patients.

Takeaway

This study looked at 10 patients with a rare type of thyroid cancer. Some of them lived a long time after surgery, even though their cancer was serious.

Methodology

The study reviewed surgical and pathological records of patients diagnosed with papillary thyroid carcinoma with squamous cell carcinoma components.

Limitations

The study is limited by the small sample size and the rarity of the condition.

Participant Demographics

The participants included 7 females and 3 males, aged between 68 and 83 years.

Digital Object Identifier (DOI)

10.1155/2012/230283

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