An autopsy study of maternal mortality in Mozambique: The contribution of infectious diseases
2008

Maternal Mortality in Mozambique: The Role of Infectious Diseases

Sample size: 139 publication 10 minutes Evidence: high

Author Information

Author(s): Clara Menéndez, Cleofé Romagosa, Ismail Mamudo R, Carla Carrilho, Francisco Saute, Nafissa Osman, Fernanda Machungo, Azucena Bardaji, Llorenç Quintó, Alfredo Mayor, Denise Naniche, Carlota Dobaño, Pedro L Alonso, Jaume Ordi

Primary Institution: Barcelona Center for International Health Research (CRESIB) and Department of Pathology, Hospital Clinic, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Spain

Hypothesis

What are the causes of maternal death in Mozambique?

Conclusion

Infectious diseases accounted for at least half of all maternal deaths in a tertiary hospital in Mozambique, highlighting the need for effective prevention tools.

Supporting Evidence

  • Obstetric complications accounted for 38.2% of deaths, with hemorrhage being the most frequent cause.
  • Nonobstetric conditions accounted for 56.1% of deaths, with HIV/AIDS and severe malaria being significant contributors.
  • 52.8% of the women tested were HIV-positive, indicating a high prevalence in this population.

Takeaway

Many women in Mozambique die from infections during or after pregnancy, but we can help prevent these deaths with better treatments and care.

Methodology

The study involved complete autopsies of maternal deaths at a tertiary hospital in Maputo, Mozambique, over a period of 26 months.

Potential Biases

The study may over-represent certain causes of death due to the nature of the referral hospital.

Limitations

Results may not reflect the wider community as the study was conducted in a referral hospital.

Participant Demographics

Mean age of participants was 26.1 years, with a mean parity of 2.8 births.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pmed.0050044

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