Cancer risk among residents of Rhineland-Palatinate winegrowing communities: a cancer-registry based ecological study
2008

Cancer Risk in Winegrowing Communities

Sample size: 503 publication 10 minutes Evidence: moderate

Author Information

Author(s): Andreas Seidler, Gaël Paul Hammer, Gabriele Husmann, Jochem König, Anne Krtschil, Irene Schmidtmann, Maria Blettner

Primary Institution: Federal Institute for Occupational Safety and Health (BAuA), Berlin, Germany

Hypothesis

Is there an increased cancer risk among residents of Rhineland-Palatinate winegrowing communities due to viniculture?

Conclusion

The study suggests a potentially increased risk of skin cancer, bladder cancer, and endocrine-related tumors in winegrowing communities, but the findings are not conclusive for a causal relationship.

Supporting Evidence

  • Non-melanoma skin cancer risk is significantly higher in winegrowing communities.
  • Prostate cancer and bladder cancer risks are also elevated in these areas.
  • Lung cancer risk is significantly reduced in communities with a large area under cultivation.

Takeaway

People living in areas where a lot of wine is grown might get more skin and bladder cancer, but we can't be sure why.

Methodology

The study used cancer registry data to calculate incidence rate ratios for different levels of wine cultivation in communities.

Potential Biases

The study may be affected by incomplete cancer registry data and confounding factors not accounted for.

Limitations

The ecological study design limits the ability to link individual exposure to disease, and there is a problem of multiple testing.

Participant Demographics

The study included residents from 503 winegrowing communities in Rhineland-Palatinate, Germany.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI 1.20–1.45

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1745-6673-3-12

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