Analysis of Risk Factors for Malignant Papillary Breast Lesions
Author Information
Author(s): Hanyu Zhang, Anbang Hu, Yanling Li, Mingcui Li, Zhiyuan Rong, Weilun Cheng, Yansong Liu, Yunqiang Duan, Jianyuan Feng, Ziang Chen, Tianshui Yu, Jiarui Zhang, Ting Wang, Yuhang Shang, Zhengbo Fang, Jiangwei Liu, Fanjing Kong, Fei Ma, Baoliang Guo
Primary Institution: Department of General Surgery, Second Affiliated Hospital of Harbin Medical University
Hypothesis
What are the independent risk factors associated with malignant papillary breast lesions?
Conclusion
Patients without risk factors for papillary lesions can manage their health with imaging surveillance, while those with risk factors may benefit from surgical treatment.
Supporting Evidence
- Older patients (≥ 50 years) are at a higher risk of malignant PBLs.
- Palpable tumors are associated with a higher likelihood of malignancy.
- Tumor size ≥ 15 mm significantly increases the risk of malignancy.
- Peripheral tumors have a higher probability of being malignant compared to central tumors.
- Tumors with calcification are more likely to be malignant.
Takeaway
If you have certain signs like being older than 50 or having a lump, you might need more tests for breast issues, but if you don't have those signs, you can just keep an eye on it.
Methodology
A retrospective review of clinical variables in 2964 patients with papillary lesions.
Limitations
The study is a single-center retrospective analysis.
Participant Demographics
Patients included were diagnosed with papillary lesions, with a significant portion being postmenopausal and over 50 years old.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI 2.131–3.483
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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