Economic Value of Dengue Vaccine in Thailand
Author Information
Author(s): Bruce Y. Lee, Diana L. Connor, Sarah B. Kitchen, Kristina M. Bacon, Mirat Shah, Shawn T. Brown, Rachel R. Bailey, Yongjua Laosiritaworn, Donald S. Burke, Derek A. T. Cummings
Primary Institution: University of Pittsburgh School of Medicine
Hypothesis
What is the potential economic value of administering a dengue vaccine to individuals in Thailand?
Conclusion
Vaccination against dengue is cost-effective, especially at lower vaccination costs and higher vaccine efficacy.
Supporting Evidence
- A dengue vaccine could be highly cost-effective if priced below $60.
- Vaccination at a cost of $1.50 could even be cost-saving.
- Vaccination remains cost-effective for a wide range of efficacies and costs.
- Vaccination is particularly beneficial for children under 1 year of age.
- Cost-effectiveness varies significantly with vaccine efficacy and treatment-seeking behavior.
Takeaway
This study shows that giving a dengue vaccine to babies in Thailand can save money and help prevent a lot of sickness.
Methodology
A decision analytic Markov simulation model was developed to evaluate the health and economic value of a dengue vaccine.
Potential Biases
Data inputs were derived from various sources, which may vary in quality.
Limitations
The model does not account for indirect effects of vaccination, such as herd immunity, and assumes complete compliance.
Participant Demographics
Individuals aged ≤ 1 year in Thailand.
Digital Object Identifier (DOI)
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