No Link Between Dopamine Genes and Personality Traits in Japanese People
Author Information
Author(s): Hibino Hiroyuki, Tochigi Mamoru, Otowa Takeshi, Kato Nobumasa, Sasaki Tsukasa
Primary Institution: University of Tokyo
Hypothesis
Are the DRD2, DRD3, and tyrosine hydroxylase gene polymorphisms associated with personality traits in the Japanese population?
Conclusion
The study found no evidence that the dopamine-related genes are associated with personality traits in the Japanese population.
Supporting Evidence
- The study analyzed gene polymorphisms in relation to personality traits.
- No significant associations were found after Bonferroni correction.
- The sample consisted of healthy volunteers with no major psychiatric history.
Takeaway
The researchers looked at certain genes to see if they affect personality traits, but they found no connection.
Methodology
257 healthy Japanese subjects were genotyped for specific gene polymorphisms and assessed for personality traits using standardized inventories.
Potential Biases
Potential uncontrolled socio-demographic factors could affect the results.
Limitations
The study had an unbalanced sex ratio and the sample may not represent the general population.
Participant Demographics
257 unrelated healthy volunteers (65 males and 192 females; mean age 37.3 years).
Statistical Information
P-Value
p = 0.031 (uncorrected), p = 0.048 (uncorrected), p = 0.041 (uncorrected), p = 0.015 (uncorrected), p = 0.010 (uncorrected)
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website