Antimicrobial Resistance in African Great Apes
2024

Antimicrobial Resistance in African Great Apes

Sample size: 16 publication Evidence: moderate

Author Information

Author(s): Tanga Coch Tanguy Floyde, Makouloutou-Nzassi Patrice, Mbehang Nguema Pierre Philippe, Düx Ariane, Lendzele Sevidzem Silas, Mavoungou Jacques François, Leendertz Fabian H., Mintsa-Nguema Rodrigue

Primary Institution: Research Institute for Tropical Ecology (IRET/CENAREST), Libreville, Gabon

Hypothesis

Can African great apes serve as indicators and reservoirs for the spread of antimicrobial resistance (AMR) due to their proximity to humans?

Conclusion

The study found that while AMR is prevalent in African great apes, significant gaps remain in understanding the processes behind it.

Supporting Evidence

  • All studies detected AMR in African great apes.
  • Resistance to beta-lactams was the most common, followed by aminoglycosides and tetracyclines.
  • AGAs in habitats with higher human contact showed increased levels of AMR.
  • Significant gaps remain in understanding the transmission of AMR in AGAs.

Takeaway

This study looks at how antibiotic-resistant germs are found in African great apes, which could help us understand how these germs spread to humans.

Methodology

The review analyzed 16 studies on AMR in African great apes, focusing on various habitats and levels of human interaction.

Limitations

The review highlights significant gaps in understanding the underlying processes of AMR in AGAs.

Participant Demographics

The studies included wild and captive African great apes from various locations in Africa.

Digital Object Identifier (DOI)

10.3390/antibiotics13121140

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