Neutrophil Percentage-to-Albumin Ratio as a Predictor in NSTEMI Patients
Author Information
Author(s): Karaca Mehmet, Gumusdag Ayca, Andò Giuseppe
Primary Institution: Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Education Research Hospital, University of Health Sciences Turkey
Hypothesis
This study aimed to investigate whether neutrophil percentage-to-albumin ratio (NPAR) levels on admission have prognostic significance regarding one-year major adverse cardiovascular and cerebrovascular events (MACCEs) in non-ST-elevation myocardial infarction (NSTEMI) patients.
Conclusion
The NPAR can be used as a newly identified promising inflammatory biomarker to predict one-year MACCEs in NSTEMI patients undergoing revascularization therapy.
Supporting Evidence
- Patients with MACCEs had higher CRP and neutrophil levels and lower albumin levels.
- NPAR showed better predictive performance than other inflammatory markers.
- Individuals with an NPAR value greater than 17.6 were at greater risk of developing MACCEs.
Takeaway
Doctors can use a simple blood test that looks at neutrophils and albumin to help predict if heart attack patients will have problems in the next year.
Methodology
This was a retrospective study that reviewed medical records of NSTEMI patients, measuring various blood parameters and calculating NPAR, CAR, and SII index to evaluate their association with MACCEs over a 12-month follow-up.
Potential Biases
Potential biases may arise from the retrospective nature of the study and reliance on medical records.
Limitations
The study's retrospective design and small sample size may limit the generalizability of the findings.
Participant Demographics
The cohort consisted of 464 patients with a mean age of 59.2 years, including various cardiovascular risk factors.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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