Influence of stage at diagnosis on survival differences for rectal cancer in three European populations
1999

Survival Differences in Rectal Cancer Across Europe

Sample size: 1005 publication Evidence: moderate

Author Information

Author(s): Monnet E, Faivre J, Raymond L, Garau I

Primary Institution: Department of Public Health, Faculty of Medicine and Pharmacy, France

Hypothesis

How does the stage at diagnosis affect survival rates for rectal cancer in different European populations?

Conclusion

Survival differences in rectal cancer patients are mainly due to the stage at diagnosis.

Supporting Evidence

  • In the Mallorca registry, 16% of patients were diagnosed in TNM stage I, compared to 21% in Côte d'Or and 29% in Geneva.
  • The 5-year relative survival rate was 35% in Mallorca, 47% in Côte d'Or, and 48% in Geneva.

Takeaway

Doctors found that when people in Europe get diagnosed with rectal cancer at different stages, it affects how long they live after that.

Methodology

The study analyzed rectal cancer cases from three European registries and used a multiple regression model to assess survival based on stage at diagnosis.

Participant Demographics

Patients diagnosed with rectal cancer in three European countries: Switzerland, France, and Spain.

Statistical Information

P-Value

P < 10−4

Confidence Interval

95% confidence interval 0.76–1.32 and 0.85–1.44

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690716

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