Identifying a Human Strain of Helicobacter heilmannii
Author Information
Author(s): Katri Jalava, Stephen L.W. On, Clare S. Harrington, Leif P. Andersen, Marja-Liisa Hanninen, Peter Vandamme
Primary Institution: University of Helsinki
Hypothesis
Can a cultured human Helicobacter heilmannii isolate be identified as H. bizzozeronii?
Conclusion
The study confirms that the human Helicobacter heilmannii isolate is H. bizzozeronii, indicating its zoonotic potential.
Supporting Evidence
- The human strain was identified as H. bizzozeronii, commonly found in dogs.
- Numerical comparison showed 90.9% similarity to a reference strain of H. bizzozeronii.
- Phylogenetic analysis confirmed the close relationship between the strains.
- Multiple types of gastrospirilla were found in a single patient, indicating zoonotic transmission.
Takeaway
Scientists found that a type of bacteria from humans, which is usually found in dogs, can be passed from animals to people.
Methodology
The study used phenotypic tests, protein profiling, 16S rRNA sequencing, and DNA-DNA hybridization to identify the strain.
Limitations
Further studies are needed to clarify taxonomic relationships and zoonotic potential.
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