Using Aripiprazole for Obsessive-Compulsive Disorder with Poor Insight
Author Information
Author(s): Michele Fornaro, Filippo Gabrielli, Chiara Mattei, Valentina Vinciguerra, Pantaleo Fornaro
Primary Institution: Dipartimento di Neuroscienze, Oftalmologia e Genetica (DINOG), Sezione di Psichiatria, Università di Genova, Italy
Hypothesis
Can aripiprazole be an effective augmentation strategy for patients with poor insight obsessive-compulsive disorder who do not respond to serotonin reuptake inhibitors?
Conclusion
Aripiprazole may help improve symptoms in patients with poor insight OCD who do not respond well to traditional treatments.
Supporting Evidence
- The patient showed poor response to serotonin reuptake inhibitors.
- After adding aripiprazole, there was a mild clinical improvement in OCD symptoms.
- The study highlights the need for further research on aripiprazole in OCD treatment.
Takeaway
This study looked at one patient with OCD who didn't get better with regular medicine, but felt a little better when given a different medicine called aripiprazole.
Methodology
A case report of a 34-year-old female patient with poor insight OCD treated with serotonin reuptake inhibitors and later augmented with aripiprazole.
Potential Biases
Potential bias due to the subjective nature of case reports and lack of control group.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
34-year-old female with a long history of poor insight OCD.
Digital Object Identifier (DOI)
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