Blood-Based Cardiac Biomarkers and Physical Activity
Author Information
Author(s): Shearon Jennifer, Rushing Baylie, Love Madeleine, Head Denise
Primary Institution: Washington University in St. Louis
Hypothesis
This study investigates the associations of blood-based markers of cardiovascular health with physical activity and their moderating effects on neurotrophins and hippocampal volumes.
Conclusion
Higher physical activity is linked to lower levels of cardiac biomarkers, but cardiac biomarkers do not moderate the relationship between physical activity and neurotrophin levels or hippocampal volumes.
Supporting Evidence
- Higher physical activity was associated with lower levels of cardiac biomarkers.
- There was no moderating effect of cardiac biomarkers on associations between physical activity and neurotrophin levels.
- There was no moderating effect of cardiac biomarkers on associations between physical activity and hippocampal volumes.
Takeaway
Being active can help keep your heart healthy, but heart health markers don't change how exercise affects your brain.
Methodology
Participants completed blood draws for cardiac biomarkers, a submaximal exercise test for cardiorespiratory fitness, and wore an actigraphy watch to measure physical activity.
Participant Demographics
Cognitively normal participants aged 43-85.
Statistical Information
P-Value
p=0.03
Statistical Significance
p=0.03
Digital Object Identifier (DOI)
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