Paced-Mating Increases the Number of Adult New Born Cells in the Internal Cellular (Granular) Layer of the Accessory Olfactory Bulb
2011

Paced Mating Increases New Neurons in the Accessory Olfactory Bulb of Female Rats

Sample size: 28 publication 10 minutes Evidence: high

Author Information

Author(s): Corona Rebeca Larriva-Sahd, Jorge Paredes, Raúl G.

Primary Institution: Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México

Hypothesis

Does pacing behavior during mating influence the density of new neurons in the accessory olfactory bulb of female rats?

Conclusion

Pacing behavior during mating significantly increases the density of new neurons in the internal cellular layer of the accessory olfactory bulb.

Supporting Evidence

  • Paced mating led to a significant increase in BrdU positive cells in the accessory olfactory bulb compared to non-paced mating.
  • Females that paced their mating had similar hormonal treatments as those in other groups, ruling out hormonal differences as a factor.
  • Behavioral measures indicated that paced mating resulted in fewer intromissions needed to induce physiological changes.

Takeaway

When female rats control the speed of their mating, they grow more new brain cells in a part of their brain that helps them smell.

Methodology

The study involved injecting BrdU to label new cells and comparing the density of these cells in different groups of female rats subjected to various mating conditions.

Limitations

The study only examined the effects 15 days post-mating, and the long-term survival of the new neurons was not assessed.

Participant Demographics

Twenty-eight sexually naïve female Wistar rats, aged and weight-matched.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1371/journal.pone.0019380

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