Muscle Mass and Bone Density in Dialysis Patients
Author Information
Author(s): Kiyonori Ito, Susumu Ookawara, Hidenori Sanayama, Hideo Kakuda, Chieko Kanai, Katsuo Iguchi, Mitsutoshi Shindo, Keisuke Tanno, Shun Ishibashi, Masafumi Kakei, Kaoru Tabei, Yoshiyuki Morishita
Primary Institution: Saitama Medical Center, Jichi Medical University
Hypothesis
Is there an association between psoas muscle mass index and bone mineral density in patients undergoing hemodialysis?
Conclusion
Psoas muscle mass index is positively associated with femoral neck bone mineral density in patients undergoing hemodialysis.
Supporting Evidence
- Femoral neck bone mineral density was significantly higher in males than in females.
- Positive correlations were found between femoral neck bone mineral density and psoas muscle mass index.
- Patients with decreased muscle mass may have lower bone mineral density.
Takeaway
This study found that having more muscle in the lower back is linked to stronger bones in people on dialysis.
Methodology
The study measured psoas muscle mass using CT scans and bone mineral density using dual-energy X-ray absorptiometry in patients undergoing hemodialysis.
Potential Biases
Potential bias due to the retrospective nature of the study and lack of a control group.
Limitations
The sample size was relatively small, and the study was cross-sectional, limiting causal inferences.
Participant Demographics
80 patients (45 males, 35 females; average age 71 years) undergoing hemodialysis.
Statistical Information
P-Value
0.010
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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