Protective Effects of Terminalia arjuna Extract Against Liver and Kidney Damage
Author Information
Author(s): Manna Prasenjit, Sinha Mahua, Sil Parames C
Primary Institution: Bose Institute
Hypothesis
The aqueous extract of Terminalia arjuna can protect against carbon tetrachloride-induced oxidative stress in liver and kidney tissues.
Conclusion
The study demonstrated that the aqueous extract of Terminalia arjuna protects liver and kidney tissues from oxidative stress caused by carbon tetrachloride.
Supporting Evidence
- The extract significantly reduced serum levels of liver enzymes GPT and ALP.
- Antioxidant enzyme activities were enhanced in the liver and kidney tissues after treatment with the extract.
- Levels of lipid peroxidation products were decreased in the extract-treated groups.
Takeaway
This study shows that a plant extract can help protect your liver and kidneys from damage caused by a harmful chemical.
Methodology
Mice were pretreated with the extract for one week before being exposed to carbon tetrachloride, and various biochemical markers were measured.
Potential Biases
Potential bias due to the lack of blinding in treatment administration.
Limitations
The study did not assess long-term effects or the specific active compounds in the extract.
Participant Demographics
Swiss albino male mice, body weight 20 ± 2 g.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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