Study Protocol for Allogeneic Hematopoietic Stem Cell Transplantation Survivors
Author Information
Author(s): Bevans Margaret F, Mitchell Sandra A, Barrett A John, Bishop Michael, Childs Richard, Fowler Daniel, Krumlauf Michael, Prince Patricia, Shelburne Nonniekaye, Wehrlen Leslie
Primary Institution: National Institutes of Health
Hypothesis
Functional status, psychosocial adjustment, cancer-specific quality of life, or symptoms will vary over 3 sequential annual time points as a function of 1 or more clinical covariates in patients 3 or more years following allogeneic HSCT.
Conclusion
This study will provide multidimensional patient-reported outcomes data to expand the understanding of the survivorship experience across the trajectory of allogeneic transplantation recovery.
Supporting Evidence
- The study aims to explore changes in health outcomes during survivorship.
- Participants will complete a series of questionnaires annually.
- The study will include diverse English and Spanish speaking adult patients.
Takeaway
This study looks at how people feel and function after surviving a specific type of cancer treatment called allogeneic stem cell transplantation, to help understand their recovery better.
Methodology
This is a longitudinal observational study where adults who survive at least 3 years post-transplant complete annual questionnaires about their health and quality of life.
Limitations
Challenges in recruiting and retaining a diverse and representative sample of long-term transplant survivors.
Participant Demographics
Adults who are at least 18 years old, able to read and speak English or Spanish, and have survived a minimum of 3 years post-allogeneic HSCT.
Digital Object Identifier (DOI)
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