Residual susceptibility to measles among young adults in Victoria, Australia following a national targeted measles-mumps-rubella vaccination campaign
2007

Measles Immunity in Young Adults in Victoria, Australia

Sample size: 311 publication Evidence: moderate

Author Information

Author(s): Kelly Heath, Heather Gidding, Theo Karapanagiotidis, Jennie Leydon, Michaela Riddell

Primary Institution: Victorian Infectious Diseases Reference Laboratory

Hypothesis

The study aimed to evaluate the success of a measles-mumps-rubella (MMR) immunisation campaign in addressing susceptibility to measles among young adults in Victoria.

Conclusion

The young adult MMR program had no significant effect on reducing residual susceptibility to measles among young adults in Victoria.

Supporting Evidence

  • The Victorian state serosurveys showed no significant change in immunity after the MMR campaign.
  • About 15% of young adults remained susceptible to measles post-campaign.
  • The national serosurvey indicated a significant decline in immunity among young adults.

Takeaway

The study found that many young adults in Victoria are still at risk for measles, even after a vaccination campaign.

Methodology

The study conducted serosurveys to estimate immunity among young adults born between 1968-1982 and compared results before and after the MMR campaign.

Potential Biases

Potential sampling anomalies may have affected the estimates of immunity.

Limitations

The study lacked information on individual vaccination histories and did not evaluate the campaign's planning or advertising efforts.

Participant Demographics

Young adults born between 1968 and 1982, primarily aged 20-34 years during the study.

Statistical Information

P-Value

0.006

Confidence Interval

95% CI, 79.4–87.8

Statistical Significance

p = 0.006

Digital Object Identifier (DOI)

10.1186/1471-2458-7-99

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication