Study on Carbapenem-Resistant Enterobacteriaceae in South India
Author Information
Author(s): Muacevic Alexander, Adler John R, Anbazhagan Sowmya, Krishnan E Arvindh, S Divya, Sureshkumar Mathavi
Primary Institution: Vinayaka Mission's Kirupananda Variyar Medical College and Hospital
Hypothesis
The study aimed to detect the prevalence of carbapenem-resistant Enterobacteriaceae and the genes responsible for the resistance.
Conclusion
The study found that 8.8% of Enterobacteriaceae were carbapenem-resistant, primarily due to metallo-β-lactamase mechanisms.
Supporting Evidence
- 32.1% of samples showed growth, with 38% of those being Enterobacteriaceae.
- 8.8% of Enterobacteriaceae were found to be resistant to carbapenems.
- NDM was the most common gene detected in the resistant isolates.
Takeaway
The study looked at bacteria that are hard to treat because they resist a strong type of medicine called carbapenems, finding that some of them have special genes that help them resist treatment.
Methodology
A cross-sectional study was conducted over two years, collecting and analyzing 2,152 clinical samples for the presence of carbapenem-resistant Enterobacteriaceae.
Limitations
The study was limited to a single tertiary care hospital, which may affect the generalizability of the findings.
Participant Demographics
The majority of carbapenem-resistant isolates were found in males aged 45-65 years.
Digital Object Identifier (DOI)
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