Eco-Friendly Synthesis of Quinazoline Derivatives Using Curcumin-Sensitized Titanium Dioxide
Author Information
Author(s): Alotaibi Mshari A., Alharthi Abdulrahman I., F. Qahtan Talal, Bakht Md. Afroz
Primary Institution: Prince Sattam Bin Abdulaziz University
Hypothesis
This study explores a sustainable method for synthesizing quinazoline derivatives through visible light-driven photocatalysis using curcumin-sensitized titanium dioxide nanoparticles.
Conclusion
The study demonstrates that curcumin-sensitized TiO2 is an effective and eco-friendly catalyst for synthesizing quinazoline derivatives under visible light.
Supporting Evidence
- Curcumin-sensitized TiO2 showed significantly enhanced photocatalytic activity compared to pure TiO2.
- Under optimized conditions, a 97% product yield was achieved in 40 minutes.
- The Cur-TiO2 catalyst maintained high efficiency over four consecutive cycles with minimal performance loss.
Takeaway
This research shows how we can use a natural dye to help make new chemicals using light, which is better for the environment.
Methodology
The study used a one-pot, three-component reaction involving aldehydes, urea/thiourea, and dimedone under visible light with curcumin-sensitized TiO2.
Digital Object Identifier (DOI)
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