Cholesterol Ratio Linked to Psoriasis Risk
Author Information
Author(s): Liu Xinyan, Li Keou, Huang Tingxuan, Tang Hongfeng
Primary Institution: Department of Dermatology, Shunde Hospital, The First People's Hospital of Shunde, Southern Medical University, Foshan, China
Hypothesis
Is there a correlation between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and the risk of psoriasis?
Conclusion
Higher levels of NHHR are significantly associated with an increased risk of developing psoriasis.
Supporting Evidence
- Higher NHHR levels are consistently linked to increased psoriasis risk across multiple models.
- Subgroup analyses showed no significant interaction effects on the NHHR-psoriasis relationship.
- The study utilized a large, representative sample from the NHANES database.
Takeaway
This study found that people with higher cholesterol ratios are more likely to have psoriasis, which is a skin condition.
Methodology
The study analyzed data from 17,941 participants using weighted logistic regression and restricted cubic spline curve fitting to assess the relationship between NHHR and psoriasis.
Potential Biases
Potential recall bias due to self-reported psoriasis diagnosis.
Limitations
The study relied on self-reported data for psoriasis diagnosis, which may introduce recall bias, and causality between NHHR and psoriasis onset remains undetermined.
Participant Demographics
Participants averaged 44.61 years old, with a diverse demographic including various races and education levels.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI: 1.01, 1.15
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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