Computational Biology Resources Lack Persistence and Usability
2008

Challenges in Computational Biology Resource Maintenance

publication Evidence: moderate

Author Information

Author(s): Veretnik Stella, Fink J. Lynn, Bourne Philip E.

Primary Institution: San Diego Supercomputer Center, University of California San Diego

Hypothesis

Are computational biology resources being maintained adequately for continued use?

Conclusion

Many computational biology resources are no longer active or properly maintained, leading to frustration among scientists.

Supporting Evidence

  • 14% of biology Web servers published four years ago are no longer active.
  • Many published computational methods are difficult or impossible to obtain.
  • Authors often do not respond to requests for their software.

Takeaway

This study shows that many online tools for biology research stop working over time, making it hard for scientists to use them.

Methodology

The authors reviewed the persistence of biology Web servers and shared their experiences in obtaining software for computational methods.

Potential Biases

The authors may have a bias due to their personal experiences and frustrations with resource availability.

Limitations

The study is based on the authors' experiences and does not provide comprehensive quantitative data on software availability.

Digital Object Identifier (DOI)

10.1371/journal.pcbi.1000136

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication