Effect of the H1N1 Influenza Pandemic on the Incidence of Epidemic Keratoconjunctivitis and on Hygiene Behavior: A Cross-Sectional Study
2011

Impact of H1N1 Pandemic on Eye Infection and Hygiene Practices

publication Evidence: moderate

Author Information

Author(s): Kim Hyun Su, Choi Ho Chun, Cho Belong, Lee Joon Yong, Kwon Min Jeong

Primary Institution: Seoul National University Hospital

Hypothesis

The 2009/2010 H1N1 influenza pandemic influenced hygiene behavior and the incidence of epidemic keratoconjunctivitis (EKC).

Conclusion

Hygiene behaviors improved during the pandemic, leading to a significant reduction in EKC cases, especially among teenagers.

Supporting Evidence

  • The total number of EKC patients during the pandemic period showed a decrease of 44.9%.
  • The incidence of EKC did not peak during the pandemic period.
  • Teenagers showed a 62% decrease in EKC cases during the pandemic.

Takeaway

When people washed their hands more during the flu pandemic, fewer got a type of eye infection called EKC. But after the pandemic, they stopped washing their hands as much, and the infections came back.

Methodology

The study analyzed EKC prevalence trends using t-tests comparing data from pre-pandemic, pandemic, and post-pandemic periods.

Potential Biases

Potential misclassification of EKC cases due to reliance on clinical symptoms.

Limitations

The study's cross-sectional design limits causal inferences, and the diagnosis of EKC may include non-infectious cases.

Participant Demographics

Demographics were not specified, but the study noted significant findings in teenagers.

Statistical Information

P-Value

0.002

Confidence Interval

95% CI [45,499 to 64,344]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0023444

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