Exosomes in esophageal cancer: a promising frontier for liquid biopsy in diagnosis and therapeutic monitoring
2024

Exosomes in Esophageal Cancer: A New Way to Diagnose and Monitor Treatment

publication Evidence: moderate

Author Information

Author(s): Zihan Ren, Jingsi Cao, Lingwen Ding, Xin Liu, Yan Zhang

Primary Institution: The First Hospital of Jilin University, Changchun, Jilin, China

Hypothesis

Exosomes can serve as effective biomarkers for the early diagnosis and therapeutic monitoring of esophageal cancer.

Conclusion

Exosomes show great potential in improving the diagnosis and treatment of esophageal cancer, despite challenges in clinical application.

Supporting Evidence

  • Exosomes can act as biomarkers for early diagnosis and prognosis of esophageal cancer.
  • Exosomes modulate tumor growth, metastasis, and drug resistance by delivering bioactive molecules.
  • Liquid biopsy using exosomes is less invasive and allows for real-time monitoring of cancer.

Takeaway

Exosomes are tiny bubbles that can carry important information about cancer, helping doctors find and treat esophageal cancer better.

Methodology

This review discusses the role of exosomes in esophageal cancer diagnosis and treatment, including their isolation and detection techniques.

Limitations

Challenges include purification, enrichment, and standardization of analytical methods for exosomes.

Digital Object Identifier (DOI)

10.3389/fphar.2024.1459938

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