Millisecond-level transient heating and temperature monitoring technique for ultrasound-induced thermal strain imaging
2025

New Ultrasound Technique for Heating and Monitoring Temperature

publication Evidence: high

Author Information

Author(s): Chen Mengyue, Sheng Zhiyu, Wei Ran, Zhang Bohua, Kim Howuk, Wu Huaiyu, Chu Yu, Chen Qiyang, Breon Andrew, Li Sibo, Wielgat Matthew B., Shanmuganayagam Dhanansayan, Tzeng Edith, Geng Xuecang, Kim Kang, Jiang Xiaoning

Primary Institution: North Carolina State University

Hypothesis

This study aims to develop a transient ultrasound heating and thermocouple monitoring technique at the millisecond level for ultrasound-induced thermal strain imaging (US-TSI) applications.

Conclusion

The study successfully demonstrated a millisecond-level transient heating and temperature monitoring technique utilizing a novel US-TSI probe and fast-response thermocouples.

Supporting Evidence

  • The US-TSI probe achieved a 3.9 °C temperature rise after a 25 ms heating duration in a gel phantom.
  • In vivo tests showed a 2.0 °C temperature rise after a 50 ms heating duration in a pig model.
  • The fast-response thermocouples confirmed the ability to monitor temperature changes within 50 ms.

Takeaway

Researchers created a new ultrasound device that can quickly heat tissue and measure temperature changes, which could help detect dangerous plaques in arteries.

Methodology

The study involved designing, prototyping, and characterizing a US-TSI probe, followed by in vitro phantom and in vivo animal tests to validate its performance.

Limitations

The study did not include 3D finite element simulation due to computational costs, which may limit the design validation of the heating transducer.

Digital Object Identifier (DOI)

10.7150/thno.95997

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