Cholera Incidence in Children Across Asia and Africa
Author Information
Author(s): Deen Jacqueline L., von Seidlein Lorenz, Sur Dipika, Agtini Magdarina, Lucas Marcelino E. S., Lopez Anna Lena, Kim Deok Ryun, Ali Mohammad, Clemens John D.
Primary Institution: International Vaccine Institute
Hypothesis
What is the incidence of cholera in children under 5 years of age in endemic areas of Asia and Africa?
Conclusion
Cholera incidence varies significantly across endemic areas, with children under 5 years being the most affected in all sites.
Supporting Evidence
- The incidence of cholera was lowest in Jakarta at 0.5 cases per 1000 population per year.
- Kolkata had an incidence of 1.6 cases per 1000 population per year.
- Beira had the highest incidence at 4.0 cases per 1000 population per year.
- Children under 5 years of age bore the greatest burden of cholera across all sites.
Takeaway
Cholera is a serious disease that affects many young children, especially in places like Africa and India. We found that kids get sick with cholera more often than we thought.
Methodology
Cholera surveillance was established in treatment facilities across three sites, and incidence was calculated using population census data.
Potential Biases
Potential underreporting of cases due to reliance on clinical diagnosis and health care utilization patterns.
Limitations
The surveillance sites may not be representative of the entire region, and variations in surveillance intensity could affect results.
Participant Demographics
Surveillance included residents of all ages in impoverished areas of Jakarta, Kolkata, and Beira.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website