Preventing Nausea and Vomiting After Surgery in Teens
Author Information
Author(s): Joseph V. Pergolizzi, Robert Raffa, Robert Taylor
Primary Institution: Johns Hopkins University School of Medicine
Hypothesis
Should adolescents follow pediatric or adult guidelines for preventing postoperative nausea and vomiting (PONV)?
Conclusion
Adolescents may benefit from a combination of ondansetron and transdermal scopolamine for preventing PONV.
Supporting Evidence
- Adolescents experience high rates of postoperative nausea and vomiting.
- Combination therapy of ondansetron and transdermal scopolamine is effective.
- Limited FDA-approved treatments exist for adolescent PONV.
Takeaway
This study looks at how to stop kids and teens from feeling sick after surgery. It suggests using two medicines together to help them feel better.
Methodology
Review of clinical evidence regarding ondansetron and transdermal scopolamine for PONV in adolescents.
Potential Biases
Potential bias due to lack of extensive research on adolescent PONV.
Limitations
Limited studies specifically on adolescents and reliance on pediatric and adult data.
Participant Demographics
Pediatric patients aged 6 to 14 years for one study; adolescents aged 12 to 17 years inferred for the review.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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