Preparation, Physical-Chemical Characterization, and Cytocompatibility of Polymeric Calcium Phosphate Cements
2011

Study of New Polymeric Calcium Phosphate Cements for Dental Use

Sample size: 6 publication 10 minutes Evidence: high

Author Information

Author(s): Khashaba Rania M., Moussa Mervet, Koch Christopher, Jurgensen Arthur R., Missimer David M., Rutherford Ronny L., Chutkan Norman B., Borke James L.

Primary Institution: Medical College of Georgia

Hypothesis

Incorporation of several polymeric acids into traditional calcium phosphate cements will produce formulations with promising physical, mechanical, and biological properties for dental applications.

Conclusion

Type III CPCs show promise for dental applications due to their favorable mechanical properties and biocompatibility.

Supporting Evidence

  • Type III cement showed significantly higher compressive and diametral tensile strengths compared to the control.
  • Type III cement exhibited high biocompatibility with human gingival fibroblast cells.
  • The setting time for Type III cement was found to be 9 minutes.

Takeaway

The researchers made new types of dental cement that are strong and safe for use in teeth, which could help with dental treatments.

Methodology

The study involved creating three types of polymeric calcium phosphate cements and comparing their physical, mechanical, and biological properties to a control group of zinc polycarboxylate cement.

Limitations

The study primarily focused on in vitro assessments, which may not fully represent in vivo conditions.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2011/467641

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