Organic Papers
2011
(3R,4S)-3,4-Isopropylidenedioxy-3,4-dihydro-2H-pyrrole 1-oxide
publication
Author Information
Author(s): Flores Mari Fe, Garcia Pilar, M. Garrido Narciso, Sanz Francisca, Diez David
Primary Institution: Universidad de Salamanca
Conclusion
The crystal structure determination confirms the configuration of the chiral centres as 3S,4R.
Supporting Evidence
- The crystal structure shows intermolecular C—H⋯O interactions linking the molecules into infinite zigzag chains.
- The study provides crystallographic data for a compound that has been increasingly used in literature for its biological relevance.
Takeaway
The study describes a new compound that can be used in making medicines, and it shows how the molecules are arranged in a crystal.
Methodology
The title N-oxide was obtained by intramolecular nucleophilic displacement using a one-pot procedure.
Digital Object Identifier (DOI)
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