Photodynamic therapy - achievements and prospects
1989

Photodynamic Therapy: Achievements and Prospects

Editorial Evidence: moderate

Author Information

Author(s): D. Ash, S.B. Brown

Primary Institution: Regional Radiotherapy Centre, Cookridge Hospital, Leeds

Conclusion

Photodynamic therapy (PDT) has shown curative potential for superficial malignancies and valuable palliative roles for advanced malignancies.

Supporting Evidence

  • PDT has shown high local control rates in superficial bladder cancer with minimal morbidity.
  • Patients with early lung cancer have shown a high complete response to PDT.
  • Patients with early cancer of the oesophagus have also shown a high complete response rate to PDT.

Takeaway

Photodynamic therapy uses light to help treat cancer by making the tumor cells absorb a special drug that gets activated by the light, which can kill the cancer cells.

Methodology

The treatment involves administering a photoactive drug followed by laser light delivery to the tumor region.

Limitations

PDT has not been tested against other conventional treatments to confirm its superiority.

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