Kimura Disease: A Case Report and Review of the Literature with A New Management Protocol
2010

Kimura Disease: A Case Report and Review

publication Evidence: moderate

Author Information

Author(s): Fouda Mohamed Ashraf, Gheith Osama, Refaie Ayman, El-Saeed Mohamed, Bakr Adel, Wafa Ehab, Abdelraheem Mona, Sobh Mohamed

Primary Institution: Mansoura Urology and Nephrology Center, Mansoura University, Mansoura, Egypt

Hypothesis

Kimura disease can present atypically in a middle-aged Caucasian man with secondary steroid-responsive nephrotic syndrome.

Conclusion

The patient responded well to treatment with steroids and immunosuppressants, leading to the normalization of kidney function and disappearance of proteinuria.

Supporting Evidence

  • Kimura disease is often associated with nephrotic syndrome.
  • The patient had a significant response to steroid treatment.
  • Renal biopsy confirmed early membranous nephropathy.
  • Coexisting renal disease is common in Kimura disease patients.
  • Diagnosis can be challenging and may require multiple tests.

Takeaway

Kimura disease is a rare condition that can affect people outside its typical demographic, and it can be treated effectively with certain medications.

Methodology

The case involved clinical examination, laboratory assessment, imaging studies, and biopsies to diagnose and manage the condition.

Limitations

The diagnosis of Kimura disease can be difficult and may lead to unnecessary procedures due to unfamiliarity among clinicians.

Participant Demographics

A 50-year-old male Egyptian engineer.

Digital Object Identifier (DOI)

10.4061/2010/673908

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