Evidence of Henipavirus Infection in West African Fruit Bats
2008

Henipavirus Infection in West African Fruit Bats

Sample size: 206 publication 10 minutes Evidence: moderate

Author Information

Author(s): Hayman David T. S., Suu-Ire Richard, Breed Andrew C., McEachern Jennifer A., Wang Linfa, Wood James L. N., Cunningham Andrew A.

Primary Institution: Institute of Zoology, Zoological Society of London

Hypothesis

Are henipaviruses present in fruit bats in West Africa?

Conclusion

The study found serological evidence of henipavirus infection in fruit bats in Ghana.

Supporting Evidence

  • 39% of Eidolon helvum bats tested positive for Nipah virus antibodies.
  • 22% of Eidolon helvum bats tested positive for Hendra virus antibodies.
  • The study provides the first evidence of henipavirus infection in Africa.

Takeaway

Scientists found that some fruit bats in Ghana have been infected with a virus that can make people very sick.

Methodology

Bats were captured and tested for antibodies to henipaviruses using a Luminex multiplexed binding assay.

Potential Biases

Potential bias due to the sampling method and the limited number of species tested.

Limitations

The Luminex assay has not been stringently validated with bat sera.

Participant Demographics

Bats were sampled from various habitats in Ghana, including urban and forest areas.

Statistical Information

P-Value

0.5

Confidence Interval

95% CI: 27–51%

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0002739

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