Clonal Differences between Non-Typhoidal Salmonella (NTS) Recovered from Children and Animals Living in Close Contact in The Gambia
2011

Salmonella in Children and Animals in The Gambia

Sample size: 14 publication 10 minutes Evidence: moderate

Author Information

Author(s): Dione Michel M., Ikumapayi Usman N., Saha Debasish, Mohammed Nuredin I., Geerts Stanny, Ieven Margareta, Adegbola Richard A., Antonio Martin

Primary Institution: International Trypanotolerance Centre, Banjul, The Gambia

Hypothesis

What is the role of domestic animals in the transmission of Non-Typhoidal Salmonella (NTS) to humans in rural The Gambia?

Conclusion

The study found that humans and animals in close contact do not carry genotypically similar Salmonella serovars.

Supporting Evidence

  • NTS was identified from 21 out of 210 animal sources in the households of the infected children.
  • Chickens carried NTS more frequently than sheep and goats.
  • The most common NTS serovars were S. Colindale in humans and S. Poona in animals.
  • There was no overlap in serovars or genotypes of NTS recovered from humans or animal sources in the same household.

Takeaway

The study looked at sick children and their animals to see if they had the same germs. They found that the animals had different germs than the children.

Methodology

The study used a population-based case-control surveillance design to collect samples from children and their household animals.

Potential Biases

Potential bias due to the small sample size and specific geographic focus.

Limitations

The sample size was small and limited to a specific rural area.

Participant Demographics

Children under five years of age from rural households in The Gambia.

Statistical Information

P-Value

<0.01

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pntd.0001148

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