Determinants of Neonatal Mortality at a Referral Paediatric Hospital in Angola: A Case–Control Study Using Theoretical Frameworks
2024

Causes of Neonatal Deaths in Angola

Sample size: 318 publication 10 minutes Evidence: high

Author Information

Author(s): Avelino Israel C., Van-Dúnem Joaquim, Varandas Luís

Primary Institution: Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa

Hypothesis

What are the primary causes and contributing factors of neonatal mortality among infants admitted to a pediatric hospital in Angola?

Conclusion

The study identified key factors associated with neonatal mortality, including low Apgar scores, young maternal age, home deliveries, and prolonged illness before admission.

Supporting Evidence

  • Neonatal tetanus was identified as a leading cause of neonatal mortality.
  • Infants with low Apgar scores had a significantly higher risk of mortality.
  • Young maternal age was associated with increased neonatal mortality risk.
  • Home deliveries were linked to higher neonatal mortality compared to hospital deliveries.

Takeaway

This study looked at why some babies die in the first month of life in Angola and found that things like how well they were doing at birth and how old their moms are can make a big difference.

Methodology

A matched case-control study was conducted, analyzing medical records of neonates admitted to the Neonatology Service at a pediatric hospital.

Potential Biases

Selection bias may exist due to the study being conducted at a tertiary referral center, which primarily manages severe cases.

Limitations

The study's retrospective design limits control over confounding factors and may not represent the general neonatal population in Angola.

Participant Demographics

The sample included 318 newborns, with a slight predominance of females (57.9%) and a median maternal age of 22 years.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 1.436–4.731

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/ijerph21121609

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