Heart Rate Variability and Cardiovascular Autonomic Neuropathy in Kazakhstan
Author Information
Author(s): Bekenova Nazira, Vochshenkova Tamara, Aitkaliyev Alisher, Imankulova Balkenzhe, Turgumbayeva Zhanatgul, Kassiyeva Balzhan, Benberin Valeriy, Santos Paulo, Tchounwou Paul B.
Primary Institution: Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan
Hypothesis
Can heart rate variability (HRV) be used as an indicator for the preventive assessment of cardiovascular autonomic neuropathy (CAN) in patients?
Conclusion
The study found that heart rate variability parameters can be used for preventive measures in assessing cardiovascular autonomic neuropathy.
Supporting Evidence
- CAN was identified in 17.19% of the study participants.
- Diabetes mellitus was present in 30.99% of patients with CAN.
- The prevalence of CAN varied by sex and age.
- HRV parameters were assessed using 24-hour Holter electrocardiogram recordings.
- Statistical analysis showed significant differences in HRV between genders.
- The study included a large, randomly selected cohort from a single urban clinic.
- HRV is linked to cardiovascular health and can indicate autonomic dysfunction.
- Routine HRV monitoring is crucial for early intervention in metabolic changes.
Takeaway
This study looked at how heart rate changes can help doctors find heart problems early, especially in people with diabetes.
Methodology
A cross-sectional study was conducted with a representative sample of 5707 Kazakhs aged 20 years and older, using HRV measurements from 24-hour electrocardiograms.
Potential Biases
Potential biases may arise from self-reported ethnicity and the exclusion of certain health conditions.
Limitations
The study's single-center design may limit the generalizability of the findings.
Participant Demographics
Participants were Kazakhs aged 20 years and older, with a mix of healthy individuals and those with diabetes or cardiovascular diseases.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website