The first description of severe anemia associated with acute kidney injury and adult minimal change disease: a case report
2009

Severe Anemia and Acute Kidney Injury in Minimal Change Disease: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Qian Yimei, Mehandru Sushil K, Gornish Nancy, Frank Elliot

Primary Institution: Jersey Shore University Medical Center

Hypothesis

Can severe anemia occur in patients with acute kidney injury and minimal change disease?

Conclusion

This case suggests that adult minimal change disease can present with severe anemia and that early erythropoietin therapy may aid in renal recovery.

Supporting Evidence

  • The patient presented with severe anemia and acute kidney injury, an association not previously reported.
  • Renal function recovered completely after treatment with steroids and erythropoietin.
  • The renal biopsy showed 100% foot process effacement, characteristic of minimal change disease.

Takeaway

A woman with kidney problems also had severe anemia, which is unusual. Treating her with a medicine called erythropoietin helped her kidneys get better.

Methodology

The patient was treated with hemodialysis, erythropoietin, and corticosteroids, followed by a renal biopsy.

Limitations

The findings are based on a single case report, limiting generalizability.

Participant Demographics

60-year-old Indian-American woman with a history of hypertension and diabetes.

Digital Object Identifier (DOI)

10.1186/1752-1947-3-20

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication