Liver Cancer Stem Cells
2011
Liver Cancer Stem Cells
publication
Evidence: moderate
Author Information
Author(s): Mikhail Sameh, He Aiwu
Primary Institution: Lombardi Comprehensive Cancer Center, Georgetown University Hospital
Hypothesis
Liver cancer is a disease of adult stem cells.
Conclusion
Targeting liver cancer stem cells may bring hope to curing hepatocellular carcinoma.
Supporting Evidence
- Hepatocellular carcinoma is the most common primary malignancy of the liver in adults.
- There may be at least three distinct cell lineages with progenitor properties susceptible to neoplastic transformation.
- Targeting liver cancer stem cells may bring hope in curing hepatocellular carcinoma.
Takeaway
Liver cancer comes from special cells that can turn into cancer, and scientists are trying to find ways to stop these cells to help people get better.
Methodology
The study reviews recent research on liver cancer stem cells and their characteristics.
Limitations
It remains unclear how much overlap there is between various markers for liver cancer stem cells.
Digital Object Identifier (DOI)
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