Comparing MINIject and iStents for Glaucoma Treatment
Author Information
Author(s): Tan Jeremy C. K., Agar Ashish, Rao Harsha L., Awad Katherin, Mansouri Kaweh
Primary Institution: Faculty of Medicine and Health, University of New South Wales
Hypothesis
Does the MINIject provide better long-term intraocular pressure reduction compared to two iStents?
Conclusion
Standalone MINIject may provide a greater and more consistent reduction in intraocular pressure compared to two iStents.
Supporting Evidence
- MINIject showed a greater reduction in intraocular pressure compared to iStent.
- The mean percentage IOP reduction at 24 months was more consistent with MINIject.
- MINIject reduced the mean number of medications used more than iStent, although not statistically significant.
Takeaway
This study looked at two different devices used to treat eye pressure in people with glaucoma. It found that one device, MINIject, worked better than the other, iStents, in lowering eye pressure over two years.
Methodology
Systematic review and meta-analysis of studies comparing MINIject and iStent with at least 24 months of follow-up.
Potential Biases
Some studies had a moderate risk of bias due to missing data and deviations from intended interventions.
Limitations
The studies included had small sample sizes and varied diagnostic criteria, which may affect the generalizability of the results.
Participant Demographics
The MINIject studies included a mix of populations, with two studies in non-White populations and one primarily Caucasian.
Statistical Information
P-Value
0.03
Confidence Interval
−10.73, −8.41
Statistical Significance
p = 0.03
Digital Object Identifier (DOI)
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