Surgical treatment of malignant involvement of the inferior vena cava
2006

Surgical Treatment of Malignant Involvement of the Inferior Vena Cava

Sample size: 11 publication Evidence: moderate

Author Information

Author(s): Castelli Patrizio, Caronno Roberto, Piffaretti Gabriele, Tozzi Matteo, Lomazzi Chiara, Dionigi Gianlorenzo, Boni Luigi, Dionigi Renzo

Primary Institution: Insubria University Hospital, Versa, Italy

Hypothesis

Can aggressive surgical management provide a chance for cure or palliation in patients with malignant involvement of the inferior vena cava?

Conclusion

Surgical management for caval tumours can be performed safely with low graft-related morbidity and good patency in carefully selected patients.

Supporting Evidence

  • All patients had symptoms from their caval involvement.
  • Mean survival was 31 months with a 100% survival rate at 1 year.
  • Late graft thrombosis or infection did not occur.

Takeaway

Doctors can safely remove cancer from a big vein in the body, which can help patients feel better and live longer.

Methodology

Retrospective review of 11 patients who underwent caval thrombectomy and/or resection for vena cava tumours over 12 years.

Potential Biases

Selection bias may exist due to the small number of carefully selected patients.

Limitations

The small sample size limits the ability to draw broad conclusions about the effectiveness of the surgery.

Participant Demographics

10 males and 1 female, mean age 57 years, range 27-72 years.

Statistical Information

Confidence Interval

95%

Digital Object Identifier (DOI)

10.1186/1477-7800-3-19

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