Paradoxical Agitation and Masseter Spasm During Propofol Procedural Sedation: A Case Report
2024

Agitation and Muscle Spasm from Propofol Sedation: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Padaki Amit S MD, MS, Uppal Prabhdeep DO, Perza Michael PharmD

Primary Institution: Baylor College of Medicine

Conclusion

Propofol can cause agitation and muscle spasms, which may lead to serious complications during sedation.

Supporting Evidence

  • Propofol is commonly used for sedation but can have unexpected side effects.
  • The patient experienced significant agitation and muscle spasms after receiving propofol.
  • Awareness of propofol's potential adverse effects can improve patient safety.
  • Similar cases of propofol causing excitotoxicity have been reported in the literature.

Takeaway

Sometimes, a medicine called propofol can make people feel really jumpy and cause their muscles to tighten up, which can be dangerous.

Methodology

A case report of a 58-year-old man who experienced adverse effects during propofol sedation for an ankle injury.

Limitations

The case report is based on a single patient, limiting generalizability.

Participant Demographics

58-year-old male with a history of obesity and gait instability.

Digital Object Identifier (DOI)

10.5811/cpcem.21283

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