Blast2GO: A Comprehensive Suite for Functional Analysis in Plant Genomics
Author Information
Author(s): Ana Conesa, Stefan Götz
Primary Institution: Centro de Investigación Príncipe Felipe
Hypothesis
Functional annotation of novel sequence data is a primary requirement for the utilization of functional genomics approaches in plant research.
Conclusion
The Blast2GO suite is a useful tool for functional annotation and data mining in plant genomics research.
Supporting Evidence
- Blast2GO has been referenced in over thirty peer-reviewed publications.
- More than 100 labs worldwide have become B2G users since its release.
- The application supports various vocabularies including gene ontology terms and KEGG pathways.
Takeaway
Blast2GO helps scientists understand the functions of plant genes by organizing and analyzing genetic data in a user-friendly way.
Methodology
The Blast2GO application uses a three-step process: blast to find homologous sequences, mapping to collect GO terms, and annotation to assign functional terms.
Limitations
The tool may not be as effective for non-model species due to the lack of available functional annotations.
Digital Object Identifier (DOI)
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