Cervical Cancer Incidence and Survival in Amsterdam
Author Information
Author(s): S Bulk, O Visser, L Rozendaal, R H M Verheijen, C J L M Meijer
Primary Institution: VU University Medical Center
Hypothesis
The incidence of adenocarcinoma of the cervix is unchanged or increasing, while squamous cell carcinoma incidence is decreasing.
Conclusion
The incidence of squamous cell carcinoma has decreased, but adenocarcinoma incidence remains unchanged, and patients with adenocarcinoma have lower survival rates compared to those with squamous cell carcinoma.
Supporting Evidence
- The annual number of cervical cancer cases decreased from 157 in 1988 to 135 in 2000.
- The European standardized rate of cervical cancer decreased from 11.8 to 8.2 per 100,000 women from 1988 to 2000.
- Patients with adenocarcinoma had a relative survival of 66%, compared to 72% for squamous cell carcinoma.
Takeaway
This study shows that fewer women are getting squamous cell carcinoma, but adenocarcinoma cases are not going down, and those patients tend to do worse.
Methodology
Data from a population-based cancer registry covering the Greater Amsterdam area was analyzed for cervical cancer cases diagnosed between 1988 and 2000.
Potential Biases
Potential bias due to lack of data on screening participation.
Limitations
Data on individual participation in cervical cancer screening was not available.
Participant Demographics
Patients diagnosed with cervical cancer in the Greater Amsterdam area, with a median age of 44 for adenocarcinoma and 47 for squamous cell carcinoma.
Statistical Information
P-Value
<0.001
Confidence Interval
95% CI: 69–75%
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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