Evaluation of Antioxidant Activity of Tetracarpidium conophorum (Müll. Arg) Hutch & Dalziel Leaves
2011

Antioxidant Activity of Tetracarpidium conophorum Leaves

publication Evidence: moderate

Author Information

Author(s): Amaeze O. U., Ayoola G. A., Sofidiya M. O., Adepoju-Bello A. A., Adegoke A. O., Coker H. A. B.

Primary Institution: University of Lagos

Hypothesis

The study aims to evaluate the antioxidant activity and bioflavonoid content of Tetracarpidium conophorum leaves.

Conclusion

The ethanol:water extract of the dried leaves showed the highest antioxidant activity, indicating the potential of T. conophorum as a source of natural antioxidants.

Supporting Evidence

  • The ethanol:water extract of the dried leaves had the highest antioxidant activity with a 50% inhibition of DPPH at a concentration of 0.017 mg/mL.
  • This extract showed nitric oxide radical inhibition activity comparable to that of rutin.
  • The methanol extract of both the dried and fresh leaves had higher phenolic, flavonoids, and proanthocyanidin content than the ethanol:water extract.

Takeaway

This study found that the leaves of a plant called Tetracarpidium conophorum can help fight bad stuff in our bodies that makes us sick.

Methodology

The study used spectrophotometric methods to determine antioxidant activity through DPPH free radical, nitric oxide radical inhibition, and ferric reducing antioxidant power assays.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2011/976701

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