Effectiveness of Compounded Bioidentical Hormone Replacement Therapy
Author Information
Author(s): Ruiz Andres D, Daniels Kelly R, Barner Jamie C, Carson John J, Frei Christopher R
Primary Institution: The University of Texas at Austin
Hypothesis
Is compounded Bioidentical Hormone Replacement Therapy effective in treating menopausal symptoms?
Conclusion
Compounded BHRT improves mood symptoms in women.
Supporting Evidence
- Women experienced a 25% decrease in emotional lability.
- Women experienced a 25% decrease in irritability.
- Women experienced a 22% reduction in anxiety.
Takeaway
This study shows that a special type of hormone therapy can help women feel better during menopause.
Methodology
Observational cohort study of women aged 18-89 receiving compounded BHRT from January 1, 2003 to April 30, 2010.
Potential Biases
Potential rater bias as patients might report improvements to please healthcare providers.
Limitations
Findings may not be generalizable due to the study being conducted in one geographical region and the sample size being insufficient to assess safety.
Participant Demographics
Women aged 18-89, mean age 52 years, with various comorbidities.
Statistical Information
P-Value
p < 0.01 for emotional lability and irritability; p = 0.01 for anxiety; p = 0.09 for night sweats; p = 0.50 for hot flashes.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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