Neuromonitoring modalities predicting neurological impairment in pediatric congenital heart disease: a systematic review
2024

Neuromonitoring in Pediatric Heart Surgery

Sample size: 2846 publication 10 minutes Evidence: moderate

Author Information

Author(s): Van Loo Liselotte, Cools Bjorn, Dereymaeker Anneleen, Jansen Katrien

Primary Institution: KU Leuven, Leuven, Belgium

Hypothesis

Can neuromonitoring modalities predict neurological impairment in children with congenital heart disease after surgery?

Conclusion

The study suggests that certain neuromonitoring techniques may help predict neurological outcomes in children undergoing surgery for congenital heart disease.

Supporting Evidence

  • 40 studies were included in the review, assessing various neuromonitoring techniques.
  • Significant heterogeneity was found in the results across studies.
  • Certain biomarkers like lactate showed potential as predictors of poor outcomes.

Takeaway

Doctors are trying to find ways to check how well kids' brains are doing after heart surgery, and some tools might help them see if kids will have problems later.

Methodology

This systematic review analyzed studies on NIRS, EEG, and biochemical biomarkers related to neurodevelopmental outcomes in children with congenital heart disease.

Potential Biases

There is a risk of bias due to the observational nature of the studies and potential confounding factors.

Limitations

The studies included were observational and varied in quality, with small sample sizes and different methodologies, making it hard to draw strong conclusions.

Participant Demographics

Children under 17 years old undergoing surgery for congenital heart disease.

Digital Object Identifier (DOI)

10.3389/fneur.2024.1502762

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