Sedated vs. Unsedated Gastroscopy in Gastric Cancer Patients
Author Information
Author(s): Yin Chengke, Sun Yiwu, Liang Jie, Sui Xin, He Zhaoyi, Song Ailing, Xu Wenjia, Zhang Lei, Sun Yufei, Zhao Jingshun, Han Fei
Primary Institution: Harbin Medical University Cancer Hospital
Hypothesis
Does the type of gastroscopy (sedated vs. unsedated) affect survival outcomes in gastric cancer patients after surgery?
Conclusion
There is no significant difference in survival outcomes or distant metastases between sedated and unsedated gastroscopy in gastric cancer patients after surgery.
Supporting Evidence
- 673 patients were enrolled in the study, with 160 in the sedated group and 513 in the unsedated group.
- After propensity score matching, there were no significant differences in survival outcomes between the two groups.
- The study confirmed that sex, pathological TNM stage, Borrmann type, adjuvant treatment, and surgical resection range were independent factors affecting survival outcomes.
Takeaway
This study found that whether patients with stomach cancer have a sedated or unsedated gastroscopy doesn't change their chances of surviving after surgery.
Methodology
This was a retrospective study comparing survival outcomes of patients with gastric cancer who underwent either sedated or unsedated gastroscopy, using propensity score matching to balance baseline variables.
Potential Biases
Potential selection bias due to the retrospective nature and the exclusion of patients with certain conditions.
Limitations
The study was a single-center retrospective analysis, which may limit the generalizability of the findings and could be influenced by unmeasured confounders.
Participant Demographics
Patients diagnosed with gastric cancer who underwent gastrectomy between January 2013 and December 2017.
Statistical Information
Confidence Interval
95% CI: 0.531–1.091 for overall survival before PSM; 95% CI: 0.564–1.355 after PSM.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website